|
|
|
|
|
|
[µ¿Á¤]Àü³²ÀÇ´ë ±è°æ±Ù ±³¼öÆÀ, ±¹Á¦ÇмúÁö GUT ³í¹® °ÔÀç |
|
|
|
Àü³²´ëÇб³ ÀÇ°ú´ëÇÐ ±è°æ±Ù ±³¼öÆÀÀÇ ³í¹® ¡®Á¾¾çÇ׿ø 90K°¡ ´ëÀå¾Ï¿¡¼ CD9/CD82 »óÈ£ÀÛ¿ë ¹× ISGylation-dependent À¯ºñÄõƾÈ(ubiquitination)¸¦ ÅëÇØ ´ëÀå¾Ï ÁøÇàÀ» ÃËÁøÇÏ´Â ¥â-cateninÀ» Á¶ÀýÇÏ¿© Ç×Á¾¾çÈ¿°ú¸¦ ³ªÅ¸³½´Ù(Glycoprotein 90K, downregulated in advanced colorectal cancer tissues, interacts with CD9/CD82 and suppresses the Wnt/¥â-catenin signal via ISGylation of ¥â-catenin)¡¯°¡ 2009³â¿¡ À̾î 2³â ¿¬¼Ó ¼Òȱâ°è ±¹Á¦ÇмúÁöÀÎ 'Gut(Impact factor 9.357)¡¯ 7¿ùÈ£¿¡ °ÔÀçµÆ´Ù.
|
|
|
|
|
|
|
|
|
|
|